The fixture will form part of the Three Lions’ preparation for Euro 2016 as the Spanish join an elite list of opposition that Roy Hodgson’s side will take on in the build up to next summer’s tournament.
Having secured qualification with Saturday’s 6-0 win in San Marino, England are set to welcome France at Wembley Stadium on Tuesday 17 November (details to be confirmed) and Germany in Berlin on Saturday 26 March (kick-off TBC).
The forthcoming meeting with Spain will be the first since the 1-0 win at Wembley in November 2011. England’s last trip to Spain came in 2009, a 2-0 loss in Seville, and November’s game will be the Three Lions’ first visit to Alicante.
Ticket details and kick-off time for the match will be confirmed to England Supporters Travel Club members in due course.